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Previous and ongoing clinical trials have
2020-06-12

Previous and ongoing clinical trials have been summarized in a recent review (Siaw-Debrah et al., 2017). To our knowledge, there are no ongoing or completed clinical trials focusing on cytokines in ICH. Published studies have focused mainly on cytokine changes in ICH patients (summarized in Table 3)
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In the pleural exudates which reflect the
2020-06-12

In the pleural exudates, which reflect the in vivo conditions, the concentrations of CysLTs and PGE2 were quite similar. However, when cancer Tirapazamine were cultured for 24 h, both analyses of cell culture medium and cell incubations with Ca2+ ionophore showed low levels of CysLTs. In contrast,
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br Introduction Plasmodium falciparum malaria
2020-06-11

Introduction Plasmodium falciparum malaria continues to be a major global cause of mortality and morbidity. Malaria treatment and control has been complicated by the emergence of resistance to widespread antimalarial drug use. The most common method for measuring antimalarial resistance is estima
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To date the role of CRF and
2020-06-11

To date, the role of CRF and CRF1+ neurons within the amygdala in the expression of anxiety-like behavior and conditioned fear, and the place where these cell populations fit into the fear-related microcircuitry already identified in the CeA, have not been fully characterized. Recent evidence suppor
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Vitamin B12 receptor br Materials and methods br
2020-06-11

Materials and methods Results and discussion Conclusions In this study, we have investigated the possibility that hierarchical phosphorylation by CK2 may play a role in cellular signal transduction. Hierarchical phosphorylation by CK2 requires multiple consensus determinants with specific s
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br Cytokines potent mediators of ILC function
2020-06-11

Cytokines – potent mediators of ILC function The different ILC players are portrayed in three categories, ILC1, ILC2 and ILC3, based on the cytokines they produce and transcription factors (TFs) that guide their differentiation [8] (Figure 1). Cytokines are the most extensively studied stimuli fo
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Within the availability of large number of
2020-06-10

Within the availability of large number of experimental data, it is easy to develop the relation between the mechanical strength and corrosive resistance of the RHA added cement concrete. The developed correlation is given in the following Eq. (4.8). This equation can be used to predict any of the p
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58 5 receptor br Acknowledgements br A subgroup
2020-06-10

Acknowledgements A subgroup of pediatric solid neoplasms, collectively referred to as small round cell tumors (SRCTs) of childhood, demonstrates undifferentiated small round cell morphological characteristics. The SRCTs include neuroblastomas, lymphomas, and several bone and soft tissue sarcoma
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br Diverse functions of ERK
2020-06-10

Diverse functions of ERK pathway Same as the other MAPK cascades, the ERK pathway is activated by several extracellular stimuli and different internal routes. ERK vitally tunes the function of various substrates in all cellular components; the nucleus, cytoplasm, membranes and the cytoskeleton. E
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Results are expressed as mean s e m
2020-06-10

Results are expressed as mean±s.e.m. Paired or unpaired Student\'s t test was used for comparisons between 2 groups and one-way ANOVA followed by Bonferroni\'s post-test for more groups. Statistical significance was assigned if p Results and discussion Variations in [Ca2+]i in cardiomyocytes loade
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Introduction Determining how genes function together as biol
2020-06-10

Introduction Determining how genes function together as biological systems is a defining challenge of the genomic era. While genome sequences reveal the DNA blueprint of organisms, deciphering how this blueprint leads to biological function is challenging due in large part to the complexity of prot
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br Conflict of interest br Acknowledgements The authors
2020-06-10

Conflict of interest Acknowledgements The authors are grateful to laboratory technician Kristina Andersson for expert technical assistance. The authors acknowledge the Swedish Research Council (Grant no. 6834), Region Skåne and Faculty of Medicine, Lund University, for financial support. In
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The occurrence of three Ag NORs per metaphase and or
2020-06-10

The occurrence of three Ag-NORs per metaphase and/or a maximum of three nucleoli per nucleus in most of the varieties may be explained by chromosomal rearrangements or unequal crossing-over events that induce the deletion of the fourth active rDNA loci. Also, the chromosome pair that showed less int
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We used two different VSMCs cell lines KSB and
2020-06-10

We used two different VSMCs cell lines, KSB and CSD (isolated from two different thoracic aortas). Rat aortic VSMCs were isolated from medial segments from thoracic rate ibuprofen msds from Wistar-Kyoto rats (six to eight weeks old, Charles River Wiga GmbH) and cultured over several passages as desc
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Interaction between neutrophils and ECs represents the first
2020-06-10

Interaction between neutrophils and ECs represents the first step of the cellular phase of the inflammatory response, and provide the best condition for the transfer of the PMNL-derived LTA4 to the ECs, leading to the transcellular formation of cysteinyl-LTs. It is intriguing therefore to think that
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