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br Materials and methods br Results br Discussion Prostate c
2023-09-11
Materials and methods Results Discussion Prostate cancer is the most common cancer in men in the United States and the second leading cause of cancer death. Therapeutic interventions include mainly: radical prostatectomy or radiation therapy (RT), with or without androgen deprivation therap
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An important observation is that this patient has
2023-09-11
An important observation is that this patient has been on ALK inhibitor for more than 4 years (51 months: 27 months on crizotinib+24 months on alectinib and on-going) and there was no evidence of disease progression in the central nervous system. The other potential driver mutation in this patient’s
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In the QFP rs T allele showed a
2023-09-11
In the QFP, rs2269657-T allele showed a significant correlation with reduced plaque density in frontal cortices (Table 2), strengthening the association with amyloid pathology. The same akt inhibitors region was shown to exhibit a statistically significant reduction of SREBF2 mRNA levels in rs22696
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In addition to it we also showed that glycine increases
2023-09-11
In addition to it, we also showed that glycine increases miR-301a expression which directly binds to PTEN 3′UTR target sites [13]. Glycine confers neuroprotection through microRNA-301a/PTEN signaling in rats cortical neurons in oxygen deprivation model [13]. Substantial studies indicate that inhibit
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Ambient levels of ppm ozone were recorded
2023-09-11
Ambient levels of 0.2ppm ozone were recorded during a recent 2017 weather event in Texas, United States (EPA, 2007). This concentration or higher levels have been used in several human clinical studies during intermittent exercise (Miller et al., 2016c). Although ozone concentration of 0.8ppm used i
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A clear link between ADR stimulation
2023-09-11
A clear link between α2-ADR stimulation and decreased respiration in β-cells is established and consistent with proteomics data. Current discoveries in islets have identified physical interactions between ADR-coupled G proteins and cellular components such as insulin vesicles and ion channels (Zhao
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br Detection and possible treatments for prostate cancer
2023-09-11
Detection and possible treatments for prostate cancer PC can be diagnosed, by screening for prostate-specific antigen (PSA) and after diagnosis, treatments may include intense observation, radical prostatectomy, radiation, chemotherapy, hormone therapy or vaccination depending on the type and sta
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The first result of this paper is parallel to the
2023-09-11
The first result of this paper is parallel to the positivity result given in [16]: Here the definition of approximate ACHE metric is the same as in [18]. See Definition 1 for details. The second result of this paper is parallel to the hdac inhibitors extension formulae given in [2]. In particular
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Additional evidence for a putative role of COXs and
2023-09-11
Additional evidence for a putative role of COXs and 5-LOX in AD derives from pharmacological studies using inhibitors of these enzymes (for review, see Firuzi and Praticò, 2006). In addition to helping delineate the pathobiological mechanisms of AD, these results raise hope for discovering novel the
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Taniyama et al reported a female with
2023-09-11
Taniyama et al. reported a female with infertility who had a homozygous T-to-A transversion at nucleotide position g.2472 in exon 3 of the CYP17A1 gene (mutation Y201N) and decreased 17-hydroxylase and 17,20-lyase activities of CTPB australia was initiated using dexamethasone to control adrenal P p
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br Patients and Methods br Results
2023-09-11
Patients and Methods Results Discussion Gjerdrum et al showed that Axl Insulin (human) recombinant expressed in yeast is required to maintain the mesenchymal-like invasiveness of metastatic breast carcinoma cells, but Axl knockdown has no effect on the cell proliferation of MDA-MB-231 cell
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br Crystal structure ACLY protein
2023-09-11
Crystal structure ACLY protein is a homotetramer of four identical subunits [9]. Each polypeptide chain contains 1101 amino-acid residues [10]. The crystal structure of full-length ACLY protein is yet unresolved. However, Sun et al. recently succeeded in crystallizing chymotrypsin-truncated human
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The growth of cancer can control
2023-09-11
The growth of cancer can control by inhibiting the rate of cell proliferation or increasing the rate of selective apoptosis and effectiveness of anticancer agents varies according to genetic constitution of cancer. Hence, we investigated the anticancer activity of arginase against different kinds of
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To clarify the molecular mechanism of maduramicin
2023-09-11
To clarify the molecular mechanism of maduramicin-induced apoptosis in chicken myocardial cells, the mRNA levels of bcl-2, bax, and cytochrome C, as well as the mRNA levels and activities of caspase-3/8/9 were determined. The mRNA expressions and activities of initiator casapase-9 and executioner ca
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Available data thus indicate that there
2023-09-11
Available data thus indicate that there are at least two ways that HMGA proteins can induce localized changes in the chromatin structure of inducible gene promoters, both of which involve positioned nucleosomes that must be “remodeled” before gene transcription can occur. The first mechanism is exem
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